Bronchodilatation increases number of particles in exhaled air in subjects with asthma

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Bronchodilatation increases number of particles in exhaled air in subjects with asthma

Background Particles in exhaled air (PEx) are derived from the small airways and are formed during airway closure and re-opening. They mainly contain surfactant; both phospholipid and protein composition in PEx resemble that of BAL. Measurements of surfactant protein A in PEx from 100 l exhaled air were shown to be highly reproducible, making the PEx a promising tool in the monitoring of asthma...

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Inhalation of cold air increases the number of inflammatory cells in the lungs in healthy subjects.

Prolonged exposure to cold air may induce a chronic asthma-like condition in healthy subjects as has been demonstrated in cross-country skiers. In the present controlled study, our aim was to elucidate further the link between cold air exposure and airway inflammation by assessing the cellular influx and mediator levels within the airways following acute exposure to cold air. Bronchoalveolar (B...

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Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma.

INTRODUCTION Inhaled anticholinergic drugs are effective bronchodilators in the treatment of COPD, and tiotropium bromide has recently been introduced as a once-daily bronchodilator for use as a maintenance treatment. Racemic glycopyrrolate is an anticholinergic drug that has been used orally to control gastric acidity, parenterally as an antisialogogue and to reverse neuromuscular blockade, an...

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Relationship between exhaled air temperature and exhaled nitric oxide in childhood asthma.

Airway inflammation is a characteristic of asthma. Exhaled nitric oxide (eNO) has been demonstrated to be related to actual levels of airway inflammation in asthmatic patients. The purpose of this study was to investigate whether the temperature of exhaled air is related to eNO levels. Temperature of exhaled air and eNO were measured in 52 asthmatic children with a cross-sectional design. A sig...

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ژورنال

عنوان ژورنال: Clinical and Translational Allergy

سال: 2013

ISSN: 2045-7022,2045-7022

DOI: 10.1186/2045-7022-3-s1-p12